Our defence against microbes depends largely on the ability of neutrophils to migrate from the blood stream to sites of infection. Although the ability of animal cells to move may be primitive, and also fundamental for a number of phenomena in biology, the cellular mechanism by which neutrophils are able to move rapidly towards the infection remains an enigma. Even though the structures of the receptors involved have been sequenced and many of the molecules involved in neutrophil adherence and traction (...) identified, the essential mechanisms that control and regulate the neutrophil motor remain obscure. Here, an outline of the fundamental inadequacies in our current understanding is given, along with some recent developments that promise to produce some significant advances. (shrink)

Ch. 1. Antropogenez -- ch. 2. Problema t︠s︡elesoobraznosti -- ch. 3. Dialektika kak geneticheskai︠a︡ logika.

A free logical analysis of singular terms couched in terms of the semantic theory of Keenan and Faltz is shown to avoid problems with both Frege's and Russell's treatments. At its heart is the proposal of Keenan and Faltz to reverse the usual mode-theoretic conception of individuals and properties, taking the latter as primitive and the former as derived therefrom. A simple extension of the notion 'property' is then shown to enable a parallel treatment of definite generics.

The study of actions is of major importance in social science regardless of whether the investigator is or isn’t a behaviorist. Actions constitute much if not all of an observational substratum which both prompts explanation and confirms prediction. Actions are of interest both as samples of what an animal can do and as symptoms of underlying structures, either psychic or physical. Doubtless, actions as symptoms of underlying structures are, in the long run, of greater importance in social science than actions (...) as samples of capacities, for to be able to predict an organism’s further performance on the basis of knowledge of capacities is not necessarily to understand the organism. Understanding actions, if it is indeed the desideratum of social science—as I take it to be—involves more, however, than the viewing of actions as symptomatic of underlying structures. Actions are obviously bearers of meaning in and for a given social context, and this meaning is for both the agent and actual or imagined spectators. Spectators can be said to do their viewing both at the time the action takes place and also, in a sense, at later times when recalling or reading reports of a now past action. (shrink)

(1979). A Comparison of Item‐ Total Point Biserial Correlation, Rasch and Alpha‐Beater Item Analysis Procedures. Educational Studies: Vol. 5, No. 3, pp. 265-273.

If we reject τις, which appears only in derivative manuscripts, then the sentence is notable in the following ways. First, the position of τι—not that it separates ἕκαστος from ὑμν, but because we expect it, if present at all, to appear as πρός ὃ τι … and ἓαστός τι in itself is a conspicuously discordant juxtaposition—hence presumably the corruption to ἓαστός τις. Second, the sense: the sentence must surely mean not that each juryman has a criterion, but that each has (...) a different criterion, that he would like to see satisfied. (shrink)

Asa Kasher and Amos Yadlin’s article is a penetrating and well argued presentation of the Israeli perspective on the military ethics of terror. It does not claim to be official Israeli policy. Yet, its philosophic theoretical exposition is evident in the Israeli practice of fighting terror. On this basis it is a practical guide to action inspired by a lucid, coherent and compelling theoretical argumentation.

Purpose. The article is aimed to outline Locke’s position on the basic principles of proper human behavior. Its implementation involves: a) review of the research literature concerning the place of anthropological motive in philosophizing and b) research of his interpretation of human nature and the role of the rational component. Theoretical basis. The author’s approach is based on the conceptual provisions of phenomenology and existentialism. Originality. The work considers the teaching of Locke as the author of the original concept of (...) human nature, which is closely related to the understanding of ethical issues. It is proved that its meaningful development involves the identification of the main components of human nature in the process of determining the basic principles of personality behavior. The original conception of the thinker on the irrational component of human nature and the ways of its rationalization is analyzed. Conclusions. It is substantiated that Locke’s philosophical heritage is not reduced to depersonalized empiricism as epistemology, and his teaching about human is not limited to the abstract study of their rational component. The thinker connects the request of his own epoch with the new vision of human and the basic principles of their behavior on the basis of rationality. Locke is looking for the ways to master the irrational component of human nature and is convinced that in the era of the scientific revolution, the basis of human behavior should be rationality. Locke considers human freedom to be one of the key moments of human nature. (shrink)

In the modern world, in an epoch of fundamental changes in outdated social systems and the emergence of new societal relationships and develpments, an epoch of unprecedentedly rapid advances in science and technology — penetration into the depths of the atom and conquest of the cosmos — questions pertaining to art become of ever broader interest. In our rapidly changing world, art has become a powerful weapon in the struggle for the souls and minds of men. One can therefore welcome (...) the major topic of this congress, as selected by the Hegel Society: the fact that it is devoted to problems of Hegelian esthetics. (shrink)

‘A is a better X than B’ is to mean the same as ‘If one is choosing an X, then, if one chooses B, one ought to choose A’ (R. M. Hare, The Language of Morals, p. 184).

From 1956, when the complex ultrastructure of meiotic chromosomes was discovered, 1 until 1985, when the isolation of meiotic chromosome cores was reported, knowledge of the molecular structure of the meiotic chromosome was at best a dream. The dissection of meiotic chromosome structures has become a realistic challenge through the arrival of isolated symptonemal complexes (SCs), monoclonal and polyclonal antibodies against SCs, the possibility for screening expression libraries for genes that encode SC proteins, the isolation of SC‐associated DNA, and the (...) development of techniques for the in situ recognition of DNA sequences in the context of the meiotic chromosome structure. (shrink)